If you are using IE8+, you have to use a command line to disable script debugging. Disabling script debugging can speed up your debugger a lot, so you might want to have it disabled unless you need it.
If you’re on a 64-bit Windows, make a batch file disable:
c:\windows\syswow64\reg add HKLM\SOFTWARE\Microsoft\VisualStudio\9.0\AD7Metrics\Engine\{F200A7E7-DEA5-11D0-B854-00A0244A1DE2} /v ProgramProvider /d {170EC3FC-4E80-40AB-A85A-55900C7C70DE} /f
enable:
c:\windows\syswow64\reg add HKLM\SOFTWARE\Microsoft\VisualStudio\9.0\AD7Metrics\Engine\{F200A7E7-DEA5-11D0-B854-00A0244A1DE2} /v ProgramProvider /d {4FF9DEF4-8922-4D02-9379-3FFA64D1D639} /f
For 32-bit windows, just remove the c:\windows\syswow64\ part.
I added these two batch files to my External Tools in VS (Tools->External Tools) for quick access.
Hopefully you find this useful!